The genotype of an organism is its complete set of genes, which provides the instructions for the development and functioning of that organism. The phenotype, on the other hand, is the observable expression of those genes, including traits such as physical appearance, behavior, and biochemical properties. The relationship between genotype and phenotype is fundamental in genetics; the genotype influences the phenotype, meaning that the traits an organism exhibits are determined by its genetic makeup. While environmental factors can also affect phenotype, the underlying genetic information is what dictates the potential traits that can be expressed. Therefore, the statement 'phenotype depends on genotype' accurately captures this relationship.